563 research outputs found

    NA62 sensitivity to heavy neutral leptons in the low scale seesaw model

    Full text link
    The sensitivity of beam dump experiments to heavy neutral leptons depends on the relative strength of their couplings to individual lepton flavours in the Standard Model. We study the impact of present neutrino oscillation data on these couplings in the minimal type I seesaw model and find that it significantly constrains the allowed heavy neutrino flavour mixing patterns. We estimate the effect that the DUNE experiment will have on these predictions. We then discuss implication that this has for the sensitivity of the NA62 experiment when operated in the beam dump mode and provide sensitivity estimates for different benchmark scenarios. We find that the sensitivity can vary by almost two orders of magnitude for general choices of the model parameters, but depends only weakly on the flavour mixing pattern within the parameter range that is preferred by neutrino oscillation data.Comment: 29 pages, 8 figures, 3 tables, version accepted by JHE

    Gene expression changes of single skeletal muscle fibers in response to modulation of the mitochondrial calcium uniporter (MCU)

    Get PDF
    The mitochondrial calcium uniporter (MCU) gene codifies for the inner mitochondrial membrane (IMM) channel responsible for mitochondrial Ca2 + uptake. Cytosolic Ca2 + transients are involved in sarcomere contraction through cycles of release and storage in the sarcoplasmic reticulum. In addition cytosolic Ca2 + regulates various signaling cascades that eventually lead to gene expression reprogramming. Mitochondria are strategically placed in close contact with the ER/SR, thus cytosolic Ca2 + transients elicit large increases in the [Ca2 +] of the mitochondrial matrix ([Ca2 +]mt). Mitochondrial Ca2 + uptake regulates energy production and cell survival. In addition, we recently showed that MCU-dependent mitochondrial Ca2 + uptake controls skeletal muscle trophism. In the same report, we dissected the effects of MCU-dependent mitochondrial Ca2 + uptake on gene expression through microarray gene expression analysis upon modulation of MCU expression by in vivo AAV infection. Analyses were performed on single skeletal muscle fibers at two time points (7 and 14 days post-AAV injection). Raw and normalized data are available on the GEO database (http://www.ncbi.nlm.nih.gov/geo/) (GSE60931)

    Perspectives to find heavy neutrinos with NA62

    Full text link
    The sensitivity of beam dump experiments to heavy neutrinos depends on the relative size of their mixings with the lepton flavours in the Standard Model. We study the impact of present neutrino oscillation data on these mixing angles in the minimal type I seesaw model. We find that current data significantly constrains the allowed heavy neutrino flavour mixing patterns. Based on this, we discuss the implications for the sensitivity of the NA62 experiment to heavy neutrinos when operated in the beam dump mode. We find that NA62 is currently the most sensitive experiment in the world for heavy neutrino masses between that of the kaon and the DD-mesons. The sensitivity can vary by almost two orders of magnitude if the heavy neutrinos exclusively couple to the tau flavour, but depends only comparably weakly on the flavour mixing pattern within the parameter range preferred by light neutrino oscillation data.Comment: Contribution to the proceedings of the 53rd Rencontres de Moriond on Electroweak Interactions and Unified Theories (2018). 6 pages, 2 figure

    Dark sectors 2016 Workshop: community report

    Get PDF
    This report, based on the Dark Sectors workshop at SLAC in April 2016, summarizes the scientific importance of searches for dark sector dark matter and forces at masses beneath the weak-scale, the status of this broad international field, the important milestones motivating future exploration, and promising experimental opportunities to reach these milestones over the next 5-10 years

    Feebly-Interacting Particles:FIPs 2020 Workshop Report

    Full text link
    With the establishment and maturation of the experimental programs searching for new physics with sizeable couplings at the LHC, there is an increasing interest in the broader particle and astrophysics community for exploring the physics of light and feebly-interacting particles as a paradigm complementary to a New Physics sector at the TeV scale and beyond. FIPs 2020 has been the first workshop fully dedicated to the physics of feebly-interacting particles and was held virtually from 31 August to 4 September 2020. The workshop has gathered together experts from collider, beam dump, fixed target experiments, as well as from astrophysics, axions/ALPs searches, current/future neutrino experiments, and dark matter direct detection communities to discuss progress in experimental searches and underlying theory models for FIPs physics, and to enhance the cross-fertilisation across different fields. FIPs 2020 has been complemented by the topical workshop "Physics Beyond Colliders meets theory", held at CERN from 7 June to 9 June 2020. This document presents the summary of the talks presented at the workshops and the outcome of the subsequent discussions held immediately after. It aims to provide a clear picture of this blooming field and proposes a few recommendations for the next round of experimental results.Comment: 240 pages, 71 figure

    Search for heavy neutral lepton production in K+ decays

    Get PDF
    A search for heavy neutral lepton production in K + decays using a data sample collected with a minimum bias trigger by the NA62 experiment at CERN in 2015 is reported. Upper limits at the 10−7 to 10−6 level are established on the elements of the extended neutrino mixing matrix |Ue4| 2 and |Uμ4| 2 for heavy neutral lepton mass in the ranges 170–448 MeV/c2 and 250–373 MeV/c2, respectively. This improves on the previous limits from HNL production searches over the whole mass range considered for |Ue4|2 and above 300 MeV/c2 for |Uμ4|2

    Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

    Get PDF
    The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of ttt\overline{t}, W+bbW+b\overline{b} and W+ccW+c\overline{c} is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 ±\pm 0.02 \mbox{fb}^{-1}. The WW bosons are reconstructed in the decays WνW\rightarrow\ell\nu, where \ell denotes muon or electron, while the bb and cc quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

    Measurement of the very rare K+π+ννˉK^+ \to \pi^+ \nu \bar\nu decay

    Get PDF
    The decay K+→π+νν¯ , with a very precisely predicted branching ratio of less than 10−10 , is among the best processes to reveal indirect effects of new physics. The NA62 experiment at CERN SPS is designed to study the K+→π+νν¯ decay and to measure its branching ratio using a decay-in-flight technique. NA62 took data in 2016, 2017 and 2018, reaching the sensitivity of the Standard Model for the K+→π+νν¯ decay by the analysis of the 2016 and 2017 data, and providing the most precise measurement of the branching ratio to date by the analysis of the 2018 data. This measurement is also used to set limits on BR(K+→π+X ), where X is a scalar or pseudo-scalar particle. The final result of the BR(K+→π+νν¯ ) measurement and its interpretation in terms of the K+→π+X decay from the analysis of the full 2016-2018 data set is presented, and future plans and prospects are reviewed
    corecore